Population eﬀect of 10-valent pneumococcal conjugate vaccine
Population eﬀect of 10-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae and non-typeable Haemophilus inﬂuenzae in Kiliﬁ , Kenya: ﬁndings from cross-sectional carriage studies
Laura L Hammitt, Donald O Akech, Susan C Morpeth, Angela Karani, Norbert Kihuha, Sammy Nyongesa, Tahreni Bwanaali, Edward Mumbo, Tatu Kamau, Shahnaaz K Sharif, J Anthony G Scott
Background The eﬀect of 7-valent pneumococcal conjugate vaccine (PCV) in developed countries was enhanced by indirect protection of unvaccinated individuals, mediated by reduced nasopharyngeal carriage of vaccine-serotype pneumococci. The potential indirect protection of 10-valent PCV (PCV10) in a developing country setting is unknown. We sought to estimate the eﬀectiveness of introduction of PCV10 in Kenya against carriage of vaccine serotypes and its eﬀect on other bacteria.
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