Rotavirus Vaccine

PI: Mauricio BArreto,ISC, Brazil and Yuri Travassos, PhD student
Funded: Brazilian MRC

A case control study of rotavirus vaccine efficacy, conducted in 4 regions in Brazil, where cases are hospitalized cases of diarrhoea with confirmed rota is stools and controls are children hospitalized with for other non vaccine related conditions; diarrhoea without rotavirus were also ascertained to the study to  answer related questions, eg risk factors for non rota diarrhoea and implications of using other diarrhoea as controls for studies of vaccine efficacy.