“Safe and efficient implementation of Dengvaxia – tackling remaining challenges”



Wellcome Trust, 183 Euston Rd, Bloomsbury, London NW1 2BE

The World Health Organisation’s Strategic Advisory Group of Experts on Immunisation recommended in July 2016 that countries should consider introduction of dengue vaccine only in national or subnational settings with a high burden of disease and to target age groups where more than 70% have been infected with dengue before. This recommendation presents national advisory boards with an unprecedented complexity for optimal vaccine introduction. Problems that hinder informed decision making on vaccine implementation include uncertainties around appropriate disease and transmission proxies to define the target population, the spatial resolution needed for such proxies, difficulties in communication of vaccination strategies with policy makers, Health officials and the public, and the design of post implementation impact studies.

This one -day Vaccine Centre meeting aims to discuss these issues among an audience with a diversity of backgrounds and to conclude on the main barriers for vaccine implementation and study designs to overcome those.


The meeting will hold a number of sessions:

  • Session 1: Dengvaxia – benefits, risks, and WHO’s recommendation for use
  • Session 2: Challenges for country level implementation
  • Session 3: Operationalising Dengvaxia and optimising its impact
  • Session 4: Post licensure monitoring
  • Session 5: Panel discussion


Speakers include:      

  • Peter Smith – Professor of Tropical Epidemiology at LSHTM and member of WHO Sage WG on Dengue Vaccines
  • Mario Recker – Associate Professor in Applied Mathematics at University of Exeter
  • Mark Jit – Professor in Vaccine Epidemiology at LSHTM
  • Kirsten Vannice – WHO focal point for WHO Sage WG on Dengue Vaccines
  • Lee Ching NG – Director of the Environmental Public Health Division of Singapore’s Environmental Health Institute and member of WHO Sage WG on Dengue Vaccines
  • Joao Paulo Toledo – Director of the Department of Communicable Diseases & Surveillance at Brazil Ministry of Health
  • Heidi Larson – Associate Professor at LSHTM and Director of The Vaccine Confidence Project
  • Ira Longini – Professor & Co-director of the Center for Statistics and Quantitative Infectious Diseases at University of Florida
  • Laurent Coudeville – Modelling director at Sanofi Pasteur
  • Neil Ferguson – Professor of Mathematical Biology and head of Department of Infectious Disease Epidemiology
  • Maina L’Azou – Lead Epidemiologist on the Dengue project at Sanofi Pasteur
  • Ole Wichmann – Head of the Immunisation Unit at Robert Koch Institute

Participation is free of charge, but registration is required.


To register  go to : https://dengvaxia-meeting.eventbrite.co.uk/


For enquires please contact:

Thembi Mhlanga